Advance Your Gel, Cream, or Ointment Formulation
Whether you plan to develop a topical or transdermal dosage form, our team helps you navigate semi-solid dosage formulation with confidence. For new and existing products alike, we utilize a comprehensive approach to drug formulation to achieve the delicate balancing act needed for lasting success. We not only focus on your compound’s formulation development, but we also look ahead to build a strong foundation for effective clinical manufacturing, packaging, and beyond.
Enhanced Topical & Transdermal Dosage Forms
Topical dosage forms target sites in at least one skin layer, gland, follicle, or underlying tissue, while transdermal dosage forms target systemic circulation and avoid first pass metabolism in the gut wall and liver. With so many components to consider, formulation development for these routes of administration presents challenges unique to the skin or mucosal membranes.
Despite these hurdles, our team has robust first-hand experience developing gel, cream, lotion, and ointment semi-solid formulations. No matter where you are in your drug development process, we’ll be here to advance your preclinical or clinical studies.
- A Semisolid Dispersion of Drug in a Hydrophilic Or Hydrophobic Base.
- Hydrogels
- Non-Aqueous Gels
- Organogels
- Thermosensitive Gels
- Ph Sensitive Gels
- One Or Two Phases, Hydrophilic Drug in An Aqueous System or Hydrophobic Drug In A Lipophilic System
- Oil In Water
- Water In Oil
- Moisturizing
- Fatty/greasy Semisolid Dosage Forms with Dissolved or Dispersed Drug
- Hydrocarbon Base
- Absorption Base
- Water Removable Base
- Water Soluble Base
Developing a Hydrogel Microneedle Array Patch
Microneedles, or micro array patches (MAPs), are an evolving technology that is set to change the way we think about transdermal drug delivery systems. MAPs provide a method to bypass the stratum corneum barrier, creating new opportunities for a large variety of compounds to be delivered through the skin.
Hydrogels are a subcategory of MAPs that can be custom tailored to fit the needs of various delivery strategies, particularly those that require extended or controlled release. Careful planning needs to go into designing a hydrogel MAP, and seemingly trivial aspects should not be underestimated. Learn more about these innovative dosage forms and delivery technologies in our whitepaper.
Integrated Laboratory Services
Find the support you need by partnering with our team as your program advances to this pivotal phase and beyond.